Whether it will become a regular

The document was released after the Garridos were sentenced.Serial sex offender Garrido, 60, who pleaded guilty to kidnapping and 13 sexual assault charges, including rape, was ordered to spend the rest of his life in prison and his wife, Nancy, 55, was given a decades-long sentence.Officers wearing camouflage gear stand during a ceremony marking Federal Police Day in Mexico City.Romney aims for White HouseMitt Romney has formally declared his candidacy to challenge President Barack Obama in next year's US election.The ex-Massachusetts governor told supporters n a farm New Hampshire that he would seek the Republican nomination to try to oust the Democratic president.Performing elephant diesAn Asian elephant that gained fame by water skiing decades ago has died, a US theme park announced.Queenie, 59 was put to sleep after her health deteriorated. The Wild Adventures park in Georgia, said the animal had suffered from declining quality of life.

THE outbreak in Germany is being caused by E coli O104, a strain of the bug that has not caused outbreaks before. It looks to be nastier than E coli O157, the strain that we are only too familiar with in Scotland, in that a much higher proportion of those infected are developing the haemolytic uraemic syndrome, the complication that affects blood cells and the kADVERTISEMENTidneys. The mortality rate also seems to be high. Already, O104 has killed 18 people - three fewer than the number who died in the Central Scotland outbreak in 1996. The outbreak is still in progress, so information is still coming in, but there are hints that brain complications may also be more common. And, of course, the German outbreak is very big. In the Sakai City outbreak in Japan in 1996, there were 7,966 cases, 2,764 microbiologically confirmed. It is to be hoped the German outbreak does not match these numbers.Why E coli O104 is so nasty will be - and already is the subject of detailed and urgent research. Its genes have already been sequenced. The results show it is related to a diarrhoea-causing African type of bacterium called an enteroaggregative strain. They also show this E coli has picked up some of the virulence genes that make E coli O157 so nasty. ? Scientists discover new strain of superbug in milk of British cows?

E. coli: other outbreaksE coli O104 is also resistant to a wide range of antibiotics. This hardly matters from the treatment point of view because antibiotics treatment should be avoided in infections caused by these kinds of E coli because it is thought their use might cause the release of toxins from the bacteria as they die. Where this new E coli comes from - has it evolved in cattle, for example, and is it living in their intestines - is a question that needs to be answered urgently. Whether it will become a regular cause of food poisoning, only time will tell. Let us hope not.? Hugh Pennington is Emeritus Professor of Bacteriology at Aberdeen University. A WOMAN who was kidnapped, raped and held captive for 18 years was so afraid of her abductors that she never tried to escape, according to court documents. Jaycee Dugard said in testimony to a United States grand jury that she was zapped with a stun gun while being taken from a South Lake Tahoe street at age 11 and kept under a blanket in a car as she was driven to the home of Phillip and Nancy Garrido.ADVERTISEMENT Ms Dugard said she heard a man laughing as he said: "I can't believe we got away with it."Garrido threatened to use the stun gun on her again and said he had vicious dogs that would attack her if she left the property.Ms Dugard was later locked inside a backyard studio without being allowed to leave for an entire year. During later years, she felt helpless because she did not know where she would go if she escaped.

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In mice with Huntington's Disease

After JM6 penetrates the red blood cells, they then send a protective signal to the brain, stabilising cell function and thus preventing brain degeneration.Gladstone Institutes spokesperson Dr Lennart Mucke, whose colleague Dr Paul Muchowski identified JM6 hailed the findings, saying: "This discovery has significant implications for two devastating diseases and suggests that the KMO enzyme is a good protein for us to target with medications in diverse neurodegenerative disorders."Explaining how JM6 works, he added: "Remarkably, JM6 does not penetrate into the brain, but works by inhibiting KMO in the blood. "The blood cells then send a protective signal to the brain, to stabilize brain-cell function and prevent neurodegeneration."The fact that the compound does not pass the so-called blood-brain barrier will facilitate testing in patients, as JM6's potential impact could be confirmed with a simple blood test. With any luck, Dr Muchowski and his colleagues could begin testing this drug in patients within the next two years."

Betfred backed for ToteTHE government has chosen British-based bookmaker Betfred to buy the Tote following a six-month auction process, according to reports.Culture Secretary Jeremy Hunt is expected to declare Betfred the provisional winner of the horseracing business, the BBC said. The deal is yet to be completed, but technicalities are expected to be sorted out by the end of the day.Evans weeps over divorceDJ Chris Evans fought back the tears as he spoke about the break-up and divorce with Billie Piper.Evans held a sell-out crowd enthralled at the Hay Festival, in mid-Wales, last night as he gave an intimate glimpse of his often tempestuous life.Manchester: Two teenage boys were being questioned today in connection with a "sickening" attack in a park in which 18 birds were beheaded. A 15-year-old was held by Greater Manchester Police (GMP) on suspicion of theft and burglary and a 13-year-old on suspicion of burglary.Cornwall: One of the world's biggest - and smelliest - flowering plants, which rarely blooms and only lasts for 48 hours when it does, has burst into life in Cornwall. The Eden Project's Titan Arum, also know as the Corpse Flower, because of its smell of rotting flesh, is 2.91m tall. DEMENTIA sufferers have been offered new hope after scientists discovered a drug which could halt the debilitating symptoms. Researchers say the new drug slows the onset of both Alzheimer's and Huntington's Disease and allows sufferers to live longer.

The drug, containing a special compound called JM6, blocks an enzyme long suspected of playing a role in both degeneratiADVERTISEMENTve diseases.By testing JM6 on mice showing symptoms of Alzheimer's disease, scientists found that it could help prevent memory loss, as well as the loss of synaptic connections between brain cells, both of which are key features of Alzheimer's. In mice with Huntington's Disease, JM6 was found to prevent brain inflammation, as well as loss of synaptic connections. In both sets of mice, JM6 was also found to prolong lifespan. Results of the experiments, published in the journal Current Biology, have raised hopes that the same enzyme could be used to halt the spread of both diseases in humans.More than 750,000 people suffer from dementia related conditions - such as Alzheimer's in the UK, two-thirds of them women. 60,000 people die from the condition every year, which costs the NHS ¡ê20billion annually. Huntington's Disease is rarer - affecting between 4,000 and 6,000 people in the UK at any one time, but is hereditary and, like Alzheimer's, incurable. Scientists from Gladstone Institutes, San Francisco, USA, discovered that JM6 works by decreasing levels of kynurenine 3-monooxygenase (KMO], an enzyme long suspected of having a part to play in both diseases.

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With loving thoughts of my dear wife

In a statement, the school authorities said that at no point was the gun actually taken into the school.It added that no-one was threatened or injured during the incident and that the gun had been handed over as a gift "apparently unintentionally". SCIENTISTS are working to identify the source of "an entirely new super-toxic" strain of E.coli, which has now infected more than 1600 people worldwide, including seven in the UK. Researchers suspect that raw tomatoes, cucumbers and lettuce may be the source of the extremely "rare" form.Bank bomb was a hoaxTHE high street bank bomb alert that sparked a three-hour stand-off with armed police was a hoax,ADVERTISEMENT tests have revealed.A device strapped to the 23-year-old suspect's leg when he walked into a Co-operative bank was "not viable". The man brought Watford town centre to a standstill yesterday.Buying plan puts civil servants in it togetherTHE government is to centralise the way it buys common goods and services in a bid to cut costs.It follows an efficiency review carried out last October by retail tycoon Sir Philip Green, which concluded the government was not making the most of its scale, buying power and credit rating.Sir Philip, the owner of Topshop and Bhs, recommended that civil servants should apply the same principles as if they were spending their own money.

THE family of murder victim Claire Webster has been told they can only change the headstone of her grave with the permission of the husband who killed her. The dead woman's brother, Peter Morris, said his family wanted to erect a new headstone in the village cemetery in Aberdeenshire where Ms Webster lies buried, erasing all references to convicted killer Malcolm Webster.Mr Morris said he had been lADVERTISEMENTeft outraged after being told by council officials that they would have to gain Webster's approval for any change to the lair.The gravestone in the small rural cemetery at Tarves reads: "With loving thoughts of my dear wife Claire J Webster BSc died 27th May 1994 aged 32" and carries an inscription from Shakespeare's Merchant Of Venice which reads: "For she is wise, if I can judge of her, and fair she is, if that mine eyes be true, and true she is, as she hath proved herself, and therefore, like herself, wise, fair and true, shall she be placed in my constant soul."Webster, 52, was found guilty at the High Court in Glasgow last month of murdering his first wife in a staged car crash in Aberdeenshire in 1994 and attempting to murder his second wife, Felicity Drumm, in New Zealand in 1999.He is due to be sentenced on 5 July.Mr Morris said the family wanted Webster's lies erased from the lair where Claire lies.

He said: "I have been told by the council authorities that he is still what they call the 'lair owner', and to change the headstone I would have to go to a convicted murderer and ask his permission to give the grave to me which I find a completely outrageous situation and something that I am not prepared to do."As far as I am concerned, when he was convicted of murder he should have lost all his rights to everything."He should have no rights to the woman's grave whom he murdered."Mr Morris added: "Not only is he the owner of the grave - but he paid for the grave through the insurance money that he claimed after he murdered my sister."He planned to kill her from the day he met her. I have also been told that if I did approach him he might want to give the grave to me because it might get him a bit time off his sentence."I don't want him to get any time off his sentence. A PRIMARY teacher in the United States received a surprise end-of-term present from one of her eight-year-old pupils - a loaded handgun. The gun was in a box of toiletries handed to the female teacher in the car park of Allamanda Elementary school in Palm Springs, Florida, by the girl pupil's grandmother on Tuesday.It is thought the girl may have put the gun in the parcel without her grandmother knowing. The teacher only discovered the .22 weapon when she arrived home.Police in Palm Beach County have since launched an investigation into the incident.

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We are looking into them

The prince, who is president of SBC, met members of the charity and the 2020 Group before the meeting.SBC chief executive Jane Wood said: "I sit on the 2020 Group and His Royal Highness was very keen to facilitate this conversation - because of his commitment to climate change - with the 2020 Group and the work it is doing."This is very much a working group session, hearing what the challenges are in Scotland across the different areas, whether it's forestry, public engagement in climate change or finance."Minister for environment and climate change, Stewart Stevenson, also attended the seminar.He said: "The 2020 group is a broadly based group from the business community who are seeking to drive the climate change agenda forward, working at a very high level but reaching out to a wide range of businesses."Climate change is going to affect many things in our society."Prince Charles was also in Harris yesterday, accompanied by his wife Camilla, the Duchess of Rothesay, to help celebrate the centenary year of the Harris Tweed Orb trademark.

During a visit to a loom shed in Stockinish, the prince tried weaving the world-famous cloth. The royal couple were also given the rare honour of officially Orb stamping a length of Harris Tweed. The trademark is normally only applied by tweed inspectors, but the royals were given the opportunity to put the legally binding mark in place during a visit to the Isle of Harris Knitwear Company at Grosebay.Prince Charles spoke briefly in Gaelic during a speech at the Leac a'Lea centre where he and the duchess met local people. US Secretary of State Hillary Clinton yesteday said that Google's allegations of Chinese hacking of its e-mail system were "very serious" and would be investigated by the FBI. Google said the hundreds of accounts affected included the personal e-mail of senior US officials.Mrs Clinton said: "These allegations are very serious. We take them seriously. We are looking into them."She declined to comment further on the ADVERTISEMENTmatter, referring questions to both Google and "to the FBI which will be conducting the investigation".

Google said on Wednesday that Gmail accounts of several hundred people, including US officials, military personnel and political activists, had been hacked. Google traced the attacks to Jinan, China, the home city of a military school linked to a more sophisticated assault 17 months ago on Google's systems.Mrs Clinton said attacks such as the one alleged by Google were a prime reason the State Department had appointed a cyber-security co-ordinator. She said: "We know this is going to be a continuing problem and, therefore, we want to be as prepared as possible to deal with these matters when they do come to our attention." A day after Google exposed the breach, China denied on Thursday that it had supported hacking. It said it was part of global efforts to combat computer security threats.Foreign ministry spokesman Hong Lei said: "Allegations that the Chinese government supports hacking activities are completely unfounded and made with ulterior motives." Google said all of the hacking victims have been notified and their accounts secured.

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